Researchers from the Animal Welfare Program have published a study on the responses of zebrafish to chemicals used to euthanize them. Zebrafish are commonly used in research, and almost every fish is euthanized at the end of the study with an overdose of the anaesthetic tricaine methanesulfonate (TMS). The study found that TMS is aversive to fish and that the alternatives metomidate hydrochloride and clove oil are more humane options. These results, and the larger issue of humane euthanasia for fish, were highlighted in an Editorial in the journal Nature.
Co-authors of the study included graduate student Devina Wong and Professors Jeffrey Richards, Nina von Keyserlingk and Dan Weary.